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Uncategorized

Congrats for Mingbo Cheng for his successful Ph.D. defense!

Ivan Costa Nov 17, 2025
Uncategorized

Hodge Laplacians and Trajectory Inference with PHLOWER accepted in Nature Methods

Ivan Costa Nov 17, 2025

Thrilled to share PHLOWER, which uses Hodge Laplacians to build trajectory-level embedding for inferring complex cellular …

Hodge Laplacians and Trajectory Inference with PHLOWER accepted in Nature Methods Read more →

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Commentary on the value of multimodal single cell sequencing for inference of gene regulatory networks out in Nature Methods

Ivan Costa Aug 15, 2023

A short take on how computational approaches leverage multimodal single cell (RNA+ATAC) for inference of regulatory …

Commentary on the value of multimodal single cell sequencing for inference of gene regulatory networks out in Nature Methods Read more →

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Paper on computational method for the detection of small DNA methylation signatures out in Genome Biology

Ivan Costa Aug 15, 2023

In a study lead by Tiago Maié, we present a computational pipeline for the detection of …

Paper on computational method for the detection of small DNA methylation signatures out in Genome Biology Read more →

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Proof-of-concept trial on tasquinimod in MPN fibrosis will be conducted as a HOVON trial

Ivan Costa Aug 15, 2023
Uncategorized

Paper on spatial map of the myocardial infarction published in Nature!

Ivan Costa Aug 15, 2022

We are delighted to have our manuscript co-lead by Zhijian Li being published in Nature! Great …

Paper on spatial map of the myocardial infarction published in Nature! Read more →

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Congratulations Zhijian Li and Ronghui Li for theirs successful Ph.D. defenses

Ivan Costa Aug 15, 2022

We are happy to have two fresh PhDs from the lab! We wish you all the …

Congratulations Zhijian Li and Ronghui Li for theirs successful Ph.D. defenses Read more →

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Integration of Multimodal single cell data with MOJITOO – Accepted at ISMB/Bioinformatics

Ivan Costa Apr 28, 2022

Our manuscript describing a fast and universal integration approach for multiome protocols was accepted as a …

Integration of Multimodal single cell data with MOJITOO – Accepted at ISMB/Bioinformatics Read more →

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Area Under the Curve for Clustering @ ECML/PKDD 2022

Ivan Costa Apr 26, 2022

The paper “The area under the ROC curve as a measure of clustering quality” was published …

Area Under the Curve for Clustering @ ECML/PKDD 2022 Read more →

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Kidney Fibrosis after COVID Infection / Study published in Cell Stem Cell

Ivan Costa Feb 1, 2022

In a recently published work, we were able to show that there is increased scarring of …

Kidney Fibrosis after COVID Infection / Study published in Cell Stem Cell Read more →

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