The Institute for Computational Genomics, RWTH Aachen (www.costalab.org) is looking for an experienced bioinformatician to perform research on inference of disease progression and integrative analysis of multiome sequencing data (scRNA-seq, scATAC-seq and spatial transcriptomics). This project will be performed in …

Bioinformatics Posdoctoral Position / Inference of Disease Progression from Multimodal Single Cell Sequencing Read more »

In a joint work, M.Sc. Zhijian Li and Prof. Ivan G. Costa, Institute for Computational Genomics, and Dr. Christoph Kuppe and Prof. Rafael Kramann, Institute for Experimental Internal Medicine and Systems Biology of the Uniklinik RWTH Aachen developed a machine …

De-noising of single cell ATAC-seq and identification of TFs driving fibrosis in Kidney with scOpen published in Nature Communications Read more »

In a joint effort, the Institute for Computational Genomics at the Uniklinik RWTH Aachen and collaborators from Ulm University (Germany) and the Cochin Institute (Paris, France) have characterized the role of the transcription factor ONECUT1 in diabetes, which was recently …

Work on genetic variants in ONECUT1 associated to diabetes accepted in Nature Medicine Read more »