We have published the first method successfully integrating histone modification and DNAse-seq profiles for identification of cell active binding sites in Bioinformatics jornal. You can find our tool to detect footprints here.
On a collaboration with the Biochemistry Institute, UK Aachen, we have used NGS data from histone modifications and transcription factors to show the role of MYC in inducing histone modification supporting gene transcription. Check the manuscript here.
Manuel Allhoff will give a talk on “Detecting differential peaks in ChIP-seq signals with ODIN” at the Hitseq workshop (http://hitseq.org/) in Boston. ODIN is a HMM-based approach to detect and analyse differential peaks in pairs of ChIP-seq data. ODIN is …
We won the award as the best research group of the medical faculty at the day of Medical Research. Congratulations to all members!
The variant detection method clever, which improves the detection of mid-range variants from DNA-Seq data, was commented in the Faculty of 1000.
Eduardo Gusmao was awarded with the Best Short Presentation at the Brazilian Bioinformatics Meeting X-meeting 2013. Congratulations Eduardo!
It is a pleasure to announce that the group has released a beta version of the python tool used to analysis of regulatory and epigenetic data. The tool includes modules for genomic data handling (bed, bam), motif analyis and ChIP-Seq …
Eduardo Gusmao will give a talk on his work on transcription factor binding site detection on open chromatin at the X-meeting 2013 and Gilderlanio Araujo will present his work on detection of risk variants on Alzheimer disease. See program here
Manuel Allhoff has recently presented a paper at Recomb-Sew on detection of motifs underling errors in sequencing from Ilumina devices. The paper is found here.
We will offer in May a practical course for analysis and modeling of gene expression in the context of biomedical applications. This course will jointly offered with Prof. Schuppert Lab from AICES, RWTH. More information on http://www.costalab.org/wp/?page_id=379 Unfortunately place were restricted, but …