In Hanzellman et al., we show how senescence-associated DNA hypermethylation occurs at specific sites in the genome and reflects functional changes in the course of replicative senescence.
Eduardo Gusmao will give a talk on the latest developments of the DNase-Seq footprinting method HINT on the Regulatory Genomics Special Interest Group at ISMB.
The Computational Biology Group of Interdisciplinary Center for Clinical Research (IZKF) Aachen, RWTH Aachen University Hospital, Aachen, invites applicants for a PhD candidate position in bioinformatics in one of the following topics: 1) Statistical machine learning methods for the analysis of medical epigenomics …
PhD Position in Bioinformatics of lncRNAs and Epigenomics (closed) Read more »
We have released the first version of the differential peak caller ODIN. Please check ODIN’s website and it’s publication for more information.
We have published the first method successfully integrating histone modification and DNAse-seq profiles for identification of cell active binding sites in Bioinformatics jornal. You can find our tool to detect footprints here.
On a collaboration with the Biochemistry Institute, UK Aachen, we have used NGS data from histone modifications and transcription factors to show the role of MYC in inducing histone modification supporting gene transcription. Check the manuscript here.
Manuel Allhoff will give a talk on “Detecting differential peaks in ChIP-seq signals with ODIN” at the Hitseq workshop (http://hitseq.org/) in Boston. ODIN is a HMM-based approach to detect and analyse differential peaks in pairs of ChIP-seq data. ODIN is …
Talk at Hitseq 2014 – Detecting differential peaks in ChIP-seq signals with ODIN Read more »
We won the award as the best research group of the medical faculty at the day of Medical Research. Congratulations to all members!
The variant detection method clever, which improves the detection of mid-range variants from DNA-Seq data, was commented in the Faculty of 1000.
Eduardo Gusmao was awarded with the Best Short Presentation at the Brazilian Bioinformatics Meeting X-meeting 2013. Congratulations Eduardo!
