New Member – Fabio Ticoni
Fabio Ticconi has just joined the group as a Ph.D. candidate. Welcome!
Author: Ivan Costa
Talk at IFCS 2015 on Detection of DNA methylation signatures
Marcelo Freitas will give a talk on the International Federation of Classification Societies. He will discuss about this lattest work on prediction of signatures from highly dimensional DNA methylation data for prediction of patient age.
Publication in Clinical Epigenetics – Senecense and Nuclear Organization
In Hanzellman et al., we show how senescence-associated DNA hypermethylation occurs at specific sites in the genome and reflects functional changes in the course of replicative senescence.
Talk in RegGen/ISMB 2015 – Detection of DNAse footprints
Eduardo Gusmao will give a talk on the latest developments of the DNase-Seq footprinting method HINT on the Regulatory Genomics Special Interest Group at ISMB.
PhD Position in Bioinformatics of lncRNAs and Epigenomics (closed)
The Computational Biology Group of Interdisciplinary Center for Clinical Research (IZKF) Aachen, RWTH Aachen University Hospital, Aachen, invites applicants for a PhD candidate position in bioinformatics in one of the following topics: 1) Statistical machine learning methods for the analysis of medical epigenomics …
PhD Position in Bioinformatics of lncRNAs and Epigenomics (closed) Read more »
Release of Differential Peak Calling Tool ODIN
We have released the first version of the differential peak caller ODIN. Please check ODIN’s website and it’s publication for more information.
Method for Detection of DNAse footprints
We have published the first method successfully integrating histone modification and DNAse-seq profiles for identification of cell active binding sites in Bioinformatics jornal. You can find our tool to detect footprints here.
Paper Published in Nucleic Acids Research
On a collaboration with the Biochemistry Institute, UK Aachen, we have used NGS data from histone modifications and transcription factors to show the role of MYC in inducing histone modification supporting gene transcription. Check the manuscript here.
Talk at Hitseq 2014 – Detecting differential peaks in ChIP-seq signals with ODIN
Manuel Allhoff will give a talk on “Detecting differential peaks in ChIP-seq signals with ODIN” at the Hitseq workshop (http://hitseq.org/) in Boston. ODIN is a HMM-based approach to detect and analyse differential peaks in pairs of ChIP-seq data. ODIN is …
Talk at Hitseq 2014 – Detecting differential peaks in ChIP-seq signals with ODIN Read more »
Prize at the Day of Medical Research RWTH Aachen
We won the award as the best research group of the medical faculty at the day of Medical Research. Congratulations to all members!