Papers in PNAS, Leukemia and Molecular Cell
A few successful collaborative efforts were recently published in top biomedical journals. With Zirkel and colleagues we used HINT footprint analysis to characterize transcription factor binding underlying DNA looping via HMGB2. With Sonntag and colleagues, we have leveraged molecular information gained in liver cancer mouse models to humans and showed how cyclins are associated to liver cancer survival. Finally, with Czech et al., we have leveraged expression data on mouse models and human samples to investigate pathways involved in distinct responses of leukemia patients to interferon treatment.