Author: Ivan Costa

Congratulations to Manuel Allhoff for his Ph.D. defense!

Manuel Allhoff has successfully defended his Informatics Ph.D. Congrats Batmanu!          

Posted in Uncategorized

Paper published on Nature Methods – Footprint Analysis of DNase-Seq data

Our paper revisiting footprinting analysis from DNase-Seq with HINT-BC has been accepted in Nature Methods. Check the paper here.

Posted in News

Paper accepted in Aging

Lin Q., Weidner C. I., Costa I. G., Marioni, R., Ferreira M. R. P. , Deary I. J., Wagner W., DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy?, Aging, accepted.

Posted in Uncategorized

Andre Camara defended his PhD

Andre Camara, who was jointly co-supervised by Prof. Ricardo Prudencio and our group, has successfully completed his Ph.D. degree at the Federal University of Pernambuco. His dissertation proposed a new methodology for prediction of drug-protein interactions by combining multiple information

Posted in Uncategorized

Uncovering regulatory networks during dendritic cell differentiation in NAR

Together with the cell biology department, we have investigated changes in histone modifications and binding of the master regulator Pu.1 during dendritic cell differentiation. We have derived a computational approach to detect further co-binding partners of PU.1 uncovering an regulatory

Posted in Uncategorized

New Member – Fabio Ticoni

Fabio Ticconi has just joined the group as a Ph.D. candidate. Welcome!

Posted in Uncategorized

Talk at IFCS 2015 on Detection of DNA methylation signatures

Marcelo Freitas will give a talk on the International Federation of Classification Societies. He will discuss about this lattest work on prediction of signatures from highly dimensional DNA methylation data for prediction of patient age.    

Posted in Uncategorized

Publication in Clinical Epigenetics – Senecense and Nuclear Organization

In Hanzellman et al., we show how senescence-associated DNA hypermethylation occurs at specific sites in the genome and reflects functional changes in the course of replicative senescence.

Posted in Uncategorized

Talk in RegGen/ISMB 2015 – Detection of DNAse footprints

Eduardo Gusmao will give a talk on the latest developments of the DNase-Seq footprinting method HINT on the Regulatory Genomics Special Interest Group at ISMB.

Posted in Uncategorized

PhD Position in Bioinformatics of lncRNAs and Epigenomics (closed)

The Computational Biology Group of Interdisciplinary Center for Clinical Research (IZKF) Aachen, RWTH Aachen University Hospital,  Aachen, invites applicants for a PhD candidate  position in bioinformatics in one of the following topics: 1) Statistical machine learning methods for the analysis of medical epigenomics

Posted in Uncategorized